PERCEPTIVE ADVISORS LLC

$5.1B reported 13(f) long value · latest quarter 2026-03-31 · CIK 1224962 · EDGAR ↗
sum of disclosed values for 2026-03-31; 0 positions carry a NULL value and are excluded from the sum, surfaced here rather than folded away
$5.1B
ALL retained default holdings for this (filer, period), including NULL-value ones
94
positions with no comparable holding in the prior quarter (kind new), 2026-03-31
20
positions absent from this quarter's filing after being held last quarter (kind exit), 2026-03-31 — inferred from absence, not a sale record
42
A quarter-end snapshot. Filed up to 45 days later, so this page is not current holdings and never a complete portfolio. what a 13F is — and is not ↓ methodology §13F ↗
FILING WINDOW OPEN
Quarter 2026-09-30: the 13F window is open until 2026-11-16. Rankings and QoQ moves that touch this quarter are provisional by construction — filers who have not yet reported are not zeros.

Position changes — into 2026-03-31

by shares · Δ value · filing link · how changes are classified §
Period
Position changes into quarter 2026-03-31
position matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match identity_reconciled_by_cusipthe reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGE classified_by_value · EXIT = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · NO CHANGE = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an ADD or a TRIM (NEW / ADD / TRIM / EXIT / NO CHANGE) · NO PRIOR = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stakederived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zeroreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricated shares_unit_mismatchPrev valueCurr valuePrev sharesCurr shares
position key pos:11142 · issuer key iss:1475 COM NEWADD+$67.7M+40,000$588M$656M1,995,9862,035,986
position key pos:10390 · issuer key iss:416 COMTRIM+$41.7M−33,000$315M$357M3,160,2003,127,200
position key pos:15965 · issuer key iss:175 SPONSORED ADRADD+$120M+450,000$231M$350M1,081,4211,531,421
position key pos:17657 · issuer key iss:2200 SHSADD+$56.2M+300,000$173M$230M7,985,4618,285,461
position key pos:17964 · issuer key cusip6:152309 SPONSORED ADSADD+$136M+2,341,269$73.0M$209M2,917,6345,258,903
position key pos:16702 · issuer key iss:1556 COMTRIM−$66.1M−172,596$273M$206M2,546,3912,373,795
position key pos:13625 · issuer key iss:45 COM NEWADD+$90.3M+714,000$101M$191M3,069,2253,783,225
position key pos:13206 · issuer key iss:1335 COMTRIM−$5.6M−84,600$167M$162M1,665,1051,580,505
position key pos:11808 · issuer key iss:635 COMTRIM+$28.7M−34,000$111M$139M4,457,9744,423,974
position key pos:13950 · issuer key iss:1497 COMTRIM+$11.8M−119,546$118M$130M1,350,4251,230,879
position key pos:13239 · issuer key iss:142 COMTRIM−$46.3M−790,267$176M$130M2,330,6511,540,384
position key pos:17702 · issuer key iss:1818 COMTRIM−$40.4M−135,629$163M$123M4,278,1804,142,551
position key pos:12369 · issuer key iss:1540 COMADD+$80.9M+7,847,896$16.1M$97.0M1,903,2459,751,141
position key pos:15950 · issuer key iss:970 COMTRIM−$17.8M−10,000$115M$97.0M1,452,7071,442,707
position key sid:sec:prov:cc436d9af4067ff4382c62284d4ff9e5 · issuer key cusip6:98985Y COMADD+$2.0M+248,228$85.9M$87.9M3,261,8503,510,078
position key pos:11739 · issuer key iss:1687 COM NEWADD+$19.0M+73,107$66.7M$85.7M11,833,53911,906,646
position key pos:13703 · issuer key iss:619 COMADD+$16.6M+1,189,895$68.0M$84.6M3,478,9444,668,839
position key pos:15075 · issuer key iss:265 COMADD+$46.1M+4,271,504$24.7M$70.8M3,162,5297,434,033
position key pos:13812 · issuer key iss:1378 COMTRIM+$23.7M−81,000$44.8M$68.4M1,476,5011,395,501
position key pos:17947 · issuer key iss:540 COMTRIM−$18.6M−85,000$78.6M$60.0M1,722,2901,637,290
position key sid:sec:prov:48ac0f50c981e01f7c5af17d58a117cf · issuer key cusip6:67080M COMADD−$9.9M+155,000$67.5M$57.5M3,555,8773,710,877
position key pos:12487 · issuer key iss:1240 COM PUTNEW+$50.8M+1,000,000$0$50.8M—1,000,000
position key sid:sec:prov:16b2967c1b0bb76b6346bfde109e0bb6 · issuer key cusip6:23284F COMADD+$6.2M+418,639$41.2M$47.5M9,680,18510,098,824
position key sid:sec:prov:d8f1dce881f876173d775baaae476159 · issuer key cusip6:02157Q COM SHSADD+$13.4M+225,500$31.8M$45.2M1,784,3932,009,893
position key sid:sec:prov:c58e51841f60c26aab31f70d6e4eabc3 · issuer key cusip6:29286M COMTRIM−$13.3M−41,570$53.0M$39.7M5,869,0765,827,506
position key sid:sec:prov:c0680e314bfe2d1131f5c3d642c67920 · issuer key cusip6:45258J COMTRIM−$11.0M−397,507$50.7M$39.7M1,994,8901,597,383
position key pos:16805 · issuer key iss:997 COM NEWTRIM−$10.4M−2,500$49.8M$39.4M87,91985,419
position key pos:11517 · issuer key iss:1003 COMNEW+$37.8M+504,000$0$37.8M—504,000
position key sid:sec:prov:5fa73bae4b4007f19790df8489a7fcc7 · issuer key cusip6:23954D COMNEW+$37.6M+1,755,799$0$37.6M—1,755,799
position key pos:12364 · issuer key iss:26 SPONSORED ADSTRIM−$25.2M−129,459$61.8M$36.6M458,343328,884
position key sid:sec:prov:990effbc09610fc927e1edc54d252d9d · issuer key cusip6:221015 COMADD+$28.2M+1,600,000$5.3M$33.5M692,4412,292,441
position key pos:12597 · issuer key iss:1545 COMTRIM−$18.7M−35,000$51.7M$33.1M315,541280,541
position key pos:16214 · issuer key iss:797 COM NEWNEW+$31.7M+1,223,000$0$31.7M—1,223,000
position key sid:sec:prov:19b9675407eb505d5af586b26c66f53a · issuer key cusip6:98420X COM NEWADD+$2.6M+423,196$25.3M$27.8M6,314,4526,737,648
position key pos:17626 · issuer key iss:860 COMADD+$11.4M+140,000$16.3M$27.7M160,000300,000
position key sid:sec:prov:fed138ced9737b90542a54b9484d2da0 · issuer key cusip6:10919W COM NEWTRIM−$7.5M−71,746$35.1M$27.5M449,290377,544
position key sid:sec:prov:de0907d604dc0fc94b1a3f8dd009ab9f · issuer key cusip6:00534A COMTRIM−$26.7M−925,863$53.8M$27.1M21,785,16620,859,303
position key pos:10212 · issuer key iss:1665 COMTRIM−$22.1M−520,659$48.5M$26.4M1,179,098658,439
position key pos:13067 · issuer key iss:210 COMADD−$1.9M+1,050$27.2M$25.3M148,900149,950
position key pos:14656 · issuer key iss:1552 COMNEW+$25.1M+258,600$0$25.1M—258,600
position key sid:sec:prov:03d750f8ea50214fdbd147c22363d0f6 · issuer key cusip6:78397T COM NEWADD+$21.6M+5,628,533$3.0M$24.6M803,2106,431,743
position key sid:sec:prov:831c753eb8a6ce9972092ec4165601d4 · issuer key cusip6:07782B SPONSORED ADSTRIM−$42.0M−262,260$66.3M$24.2M414,239151,979
position key sid:sec:prov:9e958f4e10d0d474cc9e75d42ea33a9a · issuer key cusip6:88032L COM NEWADD+$17.8M+1,008,640$5.4M$23.2M439,1421,447,782
position key sid:sec:prov:fd61a14f8c16900d70648b14bc187bfb · issuer key cusip6:05463X COMTRIM−$2.6M−86,828$25.7M$23.1M784,140697,312
position key sid:sec:prov:4b145c10f034612809a5ead021971789 · issuer key cusip6:92790C COMTRIM−$71.8M−1,871,874$94.7M$22.9M3,042,7031,170,829
position key sid:sec:prov:9f123b52d9dfa5657af06135ef52f112 · issuer key cusip6:68572M COMTRIM+$133K−89,350$21.3M$21.4M5,127,2565,037,906
position key sid:sec:prov:097fe4205cdb81b5acf642533490216f · issuer key cusip6:23306J SPONSORED ADSNEW+$20.1M+964,391$0$20.1M—964,391
position key sid:sec:prov:0d957017a1f6113a5600ce99517cee7f · issuer key cusip6:03675P COMADD+$10.7M+1,750,000$8.4M$19.0M1,675,4763,425,476
position key sid:sec:prov:c4149a9e14976bb08df8d6a0cb6dd6b6 · issuer key cusip6:869367 COM SHSNEW+$17.8M+715,307$0$17.8M—715,307
position key pos:11535 · issuer key iss:1757 COMADD+$12.4M+295,118$4.5M$16.9M513,035808,153
position key sid:sec:prov:05537d56ca21ce3a27a9a933baf06b09 · issuer key cusip6:21217B CL ATRIM−$342K−209,000$16.7M$16.4M1,464,5921,255,592
position key sid:sec:prov:fefbed769ea5db09695bd4a0f3004463 · issuer key cusip6:696389 COMTRIM−$12.7M−3,121,851$28.3M$15.6M12,050,0008,928,149
position key pos:12344 · issuer key iss:946 COMTRIM−$6.8M−2,974$19.2M$12.4M108,000105,026
position key sid:sec:prov:adbff6ad799c41f5a1fe4cddc6ffc42b · issuer key cusip6:30054Y COM SHSNEW+$10.3M+448,350$0$10.3M—448,350
position key sid:sec:prov:7715098c333bbe982e541f4b97bf5506 · issuer key cusip6:71722W COMNEW+$10.3M+925,000$0$10.3M—925,000
position key sid:sec:prov:87e5cb91aeaa35f0c2f2443d9f9aa785 · issuer key cusip6:640979 COMNEW+$10.0M+5,104,097$0$10.0M—5,104,097
position key sid:sec:prov:748c3ea2043f7dae881221f3c766e002 · issuer key cusip6:68170A COMTRIM−$27.9M−1,610,000$37.8M$9.9M2,396,330786,330
position key pos:11462 · issuer key iss:1296 COMTRIM−$38.4M−266,000$47.0M$8.6M331,05065,050
position key sid:sec:prov:4e7eb09ab13c64fd6730ede8dbc988b8 · issuer key cusip6:08659B COMADD−$9.9M+240,000$18.4M$8.4M602,944842,944
position key sid:sec:prov:bb257ab3c32f69680923bbff7b61bc99 · issuer key cusip6:67577R COMTRIM−$340K−2,489,158$8.7M$8.4M4,325,0001,835,842
position key pos:18210 · issuer key iss:263 CL AADD+$1.3M+19,000$6.0M$7.2M72,81291,812
position key pos:17149 · issuer key iss:1835 COMNEW+$7.1M+150,000$0$7.1M—150,000
position key sid:sec:prov:0d3c6673b7060f8873ebd8344c73bee8 · issuer key cusip6:86889P COM NEWNEW+$6.7M+229,393$0$6.7M—229,393
position key sid:sec:prov:fb9ea7ee3bb27d4ceeeb748915397758 · issuer key cusip6:00860C SPONSORED ADSNEW+$6.3M+600,000$0$6.3M—600,000
position key sid:sec:prov:3c1bdde45f78766466db92da273259f5 · issuer key cusip6:30052C COMNEW+$5.3M+1,286,862$0$5.3M—1,286,862
position key sid:sec:prov:26fd673c04b9acd4e799cbdab734d215 · issuer key cusip6:67576A COM CALLNEW+$4.2M+500,000$0$4.2M—500,000
position key pos:14879 · issuer key iss:3 COMTRIM−$11.9M−416,235$16.1M$4.2M883,468467,233
position key sid:sec:prov:8cb65945c1d745d32abfa3ce25a4d2e9 · issuer key cusip6:45719W COM NEWTRIM−$7.2M−3,106,568$11.1M$3.9M5,421,5682,315,000
position key pos:16706 · issuer key iss:2081 COMTRIM−$1.6M−246,744$5.4M$3.8M453,686206,942
position key sid:sec:prov:233302be8852a126d4f3dc726082a4c4 · issuer key cusip6:03753U COMNEW+$3.3M+80,956$0$3.3M—80,956
position key sid:sec:prov:626869004f126eefd6f21e4a4f5ae60f · issuer key cusip6:27966L COM NEWNEW+$2.9M+563,239$0$2.9M—563,239
position key pos:15323 · issuer key iss:37 COMNEW+$2.1M+152,500$0$2.1M—152,500
position key pos:16094 · issuer key iss:512 COMNEW+$2.0M+50,000$0$2.0M—50,000
position key sid:sec:prov:72475b3732ae8a64b486fe41b469bb0b · issuer key cusip6:696077 COM NEWTRIM+$2.5K−8,055$1.1M$1.1M70,00061,945
position key sid:sec:prov:98b422204b4d90393e978b5ebac79307 · issuer key cusip6:230770 COMTRIM−$717K−144,109$1.4M$640K341,087196,978
position key sid:sec:prov:6cea3d644720599797447228551acb50 · issuer key cusip6:30068X COMNEW+$345K+114,893$0$345K—114,893
pos:10141 PUTEXIT‡e−$134M−1,100,000$134M$01,100,000—
pos:10385EXIT‡e−$34.4M−110,529$34.4M$0110,529—
pos:11450EXIT‡e−$21.8M−124,000$21.8M$0124,000—
pos:11504EXIT‡e−$20.5M−259,545$20.5M$0259,545—
pos:12161EXIT‡e−$35.8M−450,743$35.8M$0450,743—
pos:12384EXIT‡e−$21.7M−4,185,632$21.7M$04,185,632—
pos:12517EXIT‡e−$9.0M−200,791$9.0M$0200,791—
pos:12598EXIT‡e−$5.4M−69,935$5.4M$069,935—
pos:12631EXIT‡e−$20.3M−237,342$20.3M$0237,342—
pos:13354EXIT‡e−$17.5M−220,000$17.5M$0220,000—
pos:13630EXIT‡e−$3.6M−202,400$3.6M$0202,400—
pos:13686 CALLEXIT‡e−$5.6M−500,000$5.6M$0500,000—
pos:13935EXIT‡e−$4.1M−165,713$4.1M$0165,713—
pos:14095EXIT‡e−$93.3M−979,000$93.3M$0979,000—
pos:14212EXIT‡e−$30.7M−1,136,206$30.7M$01,136,206—
pos:14877EXIT‡e−$5.4M−829,870$5.4M$0829,870—
pos:15034EXIT‡e−$15.0M−225,758$15.0M$0225,758—
pos:15144EXIT‡e−$45.8M−200,000$45.8M$0200,000—
pos:15808EXIT‡e−$15.8M−140,000$15.8M$0140,000—
pos:16881EXIT‡e−$4.3M−17,500$4.3M$017,500—
sid:sec:prov:0983c227d7f489fadce1abda0a417532EXIT‡e−$28.0M−825,890$28.0M$0825,890—
sid:sec:prov:2452fdde4d0b3fb9db6ac52c91059345EXIT‡e−$739K−108,694$739K$0108,694—
sid:sec:prov:25db868bd92949401541405f5298734dEXIT‡e−$9.7M−550,000$9.7M$0550,000—
sid:sec:prov:287679ae59495e28d5c5c22eea9bb86eEXIT‡e−$4.8M−747,193$4.8M$0747,193—

Flags: no row carries a flag.

1–20 of the 100 changes on this page

1–100 of 118 changes
Mark-to-market only (no share change) · 18

Positions whose share count is identical in both quarters; the value changed with price, not with a decision.

Positions held with no share change into quarter 2026-03-31
position matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match identity_reconciled_by_cusipthe reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGE classified_by_value · EXIT = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · NO CHANGE = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an ADD or a TRIM (NEW / ADD / TRIM / EXIT / NO CHANGE) · NO PRIOR = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stakederived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zeroreported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricated shares_unit_mismatchPrev valueCurr valuePrev sharesCurr shares
position key sid:sec:prov:6456a8a739b1b376bb8de72f440b1279 · issuer key cusip6:03237H COMNO CHANGE+$15.1M0$100M$115M8,284,8828,284,882
position key sid:sec:prov:8771e17f16590b5bd511978f2a4f7807 · issuer key cusip6:N44445 SHSNO CHANGE−$6.9M0$109M$102M10,383,45610,383,456
position key sid:sec:prov:8c4f97ba195668adc97a71db173c878f · issuer key cusip6:G59665 COMNO CHANGE+$7.2M0$82.1M$89.3M10,326,10310,326,103
position key sid:sec:prov:f31df07e345986c48938525dc4cc3840 · issuer key cusip6:63909J COMNO CHANGE+$24.3M0$24.6M$48.9M12,594,21112,594,211
position key pos:14655 · issuer key iss:2143 SHS USDNO CHANGE+$3.2M0$28.9M$32.1M170,000170,000
position key sid:sec:prov:9fd554b76cc510ac236cd887d1f06195 · issuer key cusip6:75383L COMNO CHANGE+$640K0$20.4M$21.1M673,923673,923
position key sid:sec:prov:b4fb61062116268ce297ca59ebf42283 · issuer key cusip6:04746L COMNO CHANGE+$5.0M0$14.1M$19.1M1,859,3221,859,322
position key pos:15366 · issuer key iss:416 NOTE 2.750% 8/0 PRNNO CHANGE+$1.8M0$14.1M$15.9M6,500,0006,500,000
position key sid:sec:prov:d3e1798d38ce2deff0ab7c16a87c8200 · issuer key cusip6:H5870P ORDINARY SHARESNO CHANGE+$3.3M0$9.9M$13.1M493,827493,827
position key sid:sec:prov:6298dc09e56171c0480b6cc0aa78c0e3 · issuer key cusip6:00534B COMNO CHANGE+$741K0$10.3M$11.0M9,876,5769,876,576
position key pos:17421 · issuer key iss:475 COMNO CHANGE+$360K0$4.3M$4.7M121,082121,082
position key sid:sec:prov:4dc05f0d17e502f7e6fe21a62e2414d3 · issuer key cusip6:690145 COM NEWNO CHANGE+$108K0$3.1M$3.2M833,333833,333
position key sid:sec:prov:37b91915f07af95197894a79df85a91e · issuer key cusip6:05338F COM NEWNO CHANGE−$451K0$2.5M$2.1M139,667139,667
position key sid:sec:prov:de9b2d81435d99f71f774196a3faaaf5 · issuer key cusip6:G23549 SHSNO CHANGE−$159K0$2.2M$2.1M792,696792,696
position key pos:15409 · issuer key iss:1212 COM CL ANO CHANGE+$70.0K0$1.2M$1.2M28,00028,000
position key pos:13708 · issuer key iss:1552 *W EXP 12/17/202NO CHANGE+$213K0$235K$448K250,000250,000
position key sid:sec:prov:ea6b923dce62f9f92bb1b29b6ae9b9d1 · issuer key cusip6:293602 COM NEWNO CHANGE−$33.1K0$79.7K$46.7K86,66686,666
position key sid:sec:prov:c4f97db1890f36f80c7a359d19822318 · issuer key cusip6:86889P *W EXP 08/01/203NO CHANGE−$6660$3.3K$2.7K166,666166,666

Flags: no row carries a flag.

Newest filing in this build: 2026-07-31. Per-row filing dates are on each receipt.
Truncated by Public Filings. Changes compare every position with a security identifier, new and exited included; holdings without one are counted, not compared. methodology §13F ↗

Reported positions — 2026-03-31

1–91 of 91 issuers · $5.1B disclosed value over 94 rows · 0 undisclosed-value rows
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This build carries one quarter for this manager: 2026-03-31. Notable managers carry four published quarters, others two.
Positions PERCEPTIVE ADVISORS LLC reported for the quarter ended 2026-03-31, as that filer reported them
This list carries reported issuer names and security identities, without a dated ticker mapping. Symbols are not inferred from names.a position composed from a base filing plus NEW-HOLDINGS amendments keeps every source row here; the composition's latest filed date is the one shown served from this build's published holdings (derived from the filer's own reported rows); every row resolves to its filingShare of total reported value, calculated only when the full position list has disclosed values. This is 13F long value, not total assets.value undisclosed on the filing: retained and counted, excluded from sums, never shown as $0SharesWt
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)PRAXIS PRECISION MEDICINES I · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$656M2,035,98612.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CELCUITY INC
2 positions · 2 reported rows
Rows PERCEPTIVE ADVISORS LLC reported for CELCUITY INC, as it reported them
CELCUITY INC · COM CUSIP — $357M3,127,200
CELCUITY INC · NOTE 2.750% 8/0 CUSIP — $15.9M6,500,000 PRN
$373M—7.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ASCENDIS PHARMA A/S · SPONSORED ADR CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$350M1,531,4216.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ROIVANT SCIENCES LTD · SHS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$230M8,285,4614.5%
—CENTESSA PHARMACEUTICALS PLC · SPONSORED ADS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$209M5,258,9034.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)RHYTHM PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$206M2,373,7954.0%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)SPYRE THERAPEUTICS INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$191M3,783,2253.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)NUVALENT INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$162M1,580,5053.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)EDGEWISE THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$139M4,423,9742.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)PROTAGONIST THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$130M1,230,8792.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)APOGEE THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$130M1,540,3842.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TRAVERE THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$123M4,142,5512.4%
—AMYLYX PHARMACEUTICALS INC · COM CUSIP 03237H101
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$115M8,284,8822.3%
—IMMATICS N.V · SHS CUSIP N44445109
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$102M10,383,4562.0%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)RELAY THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$97.0M9,751,1411.9%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)INHIBRX BIOSCIENCES INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$97.0M1,442,7071.9%
—MEIRAGTX HLDGS PLC · COM CUSIP G59665102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$89.3M10,326,1031.7%
—ZYMEWORKS INC · COM CUSIP 98985Y108
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$87.9M3,510,0781.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)SOLID BIOSCIENCES INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$85.7M11,906,6461.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)DYNE THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$84.6M4,668,8391.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)BIOCRYST PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$70.8M7,434,0331.4%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ORUKA THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$68.4M1,395,5011.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ARTIVION INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$60.0M1,637,2901.2%
—NURIX THERAPEUTICS INC · COM CUSIP 67080M103
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$57.5M3,710,8771.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)MODERNA INC · COM · PUT CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$50.8M1,000,0001.0%
—NAUTILUS BIOTECHNOLOGY INC · COM CUSIP 63909J108
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$48.9M12,594,2111.0%
—CYTOMX THERAPEUTICS INC. · COM CUSIP 23284F105
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$47.5M10,098,8240.9%
—ALTO NEUROSCIENCE INC · COM SHS CUSIP 02157Q109
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$45.2M2,009,8930.9%
—ENGENE HOLDINGS INC · COM CUSIP 29286M105
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$39.7M5,827,5060.8%
—IMMUNOVANT INC · COM CUSIP 45258J102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$39.7M1,597,3830.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)INTUITIVE SURGICAL INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$39.4M85,4190.8%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)IONIS PHARMACEUTICALS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$37.8M504,0000.7%
—DAY ONE BIOPHARMACEUTICALS I · COM CUSIP 23954D109
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$37.6M1,755,7990.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ABIVAX SA · SPONSORED ADS CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$36.6M328,8840.7%
—CORVUS PHARMACEUTICALS INC · COM CUSIP 221015100
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$33.5M2,292,4410.7%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)REPLIGEN CORP · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$33.1M280,5410.6%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)JAZZ PHARMACEUTICALS PLC · SHS USD CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$32.1M170,0000.6%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)DAMORA THERAPEUTICS INC · COM NEW CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$31.7M1,223,0000.6%
—X4 PHARMACEUTICALS INC · COM NEW CUSIP 98420X202
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$27.8M6,737,6480.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)GUARDANT HEALTH INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$27.7M300,0000.5%
—BRIGHT MINDS BIOSCIENCES INC · COM NEW CUSIP 10919W405
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$27.5M377,5440.5%
—INVIVYD INC · COM CUSIP 00534A102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$27.1M20,859,3030.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)SIONNA THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$26.4M658,4390.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)REVOLUTION MEDICINES INC
2 positions · 2 reported rows
Rows PERCEPTIVE ADVISORS LLC reported for REVOLUTION MEDICINES INC, as it reported them
REVOLUTION MEDICINES INC · COM CUSIP — $25.1M258,600
REVOLUTION MEDICINES INC · *W EXP 12/17/202 CUSIP — $448K250,000
$25.6M508,6000.5%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)AXSOME THERAPEUTICS INC. · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$25.3M149,9500.5%
—SAB BIOTHERAPEUTICS INC · COM NEW CUSIP 78397T202
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$24.6M6,431,7430.5%
—BELITE BIO INC · SPONSORED ADS CUSIP 07782B104
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$24.2M151,9790.5%
—TENAX THERAPEUTICS INC · COM NEW CUSIP 88032L605
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$23.2M1,447,7820.5%
—AXOGEN INC · COM CUSIP 05463X106
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$23.1M697,3120.5%
—VIRIDIAN THERAPEUTICS INC · COM CUSIP 92790C104
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$22.9M1,170,8290.4%
—ORCHESTRA BIOMED HLDGS INC · COM CUSIP 68572M106
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$21.4M5,037,9060.4%
—RAPPORT THERAPEUTICS INC · COM CUSIP 75383L102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$21.1M673,9230.4%
—DBV TECHNOLOGIES S A · SPONSORED ADS CUSIP 23306J309
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$20.1M964,3910.4%
—LEONABIO INC · COM CUSIP 04746L203
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$19.1M1,859,3220.4%
—ANTERIS TECHNOLOGIES GLOBAL · COM CUSIP 03675P102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$19.0M3,425,4760.4%
—SUTRO BIOPHARMA INC · COM SHS CUSIP 869367201
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$17.8M715,3070.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TANGO THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$16.9M808,1530.3%
—CONTINEUM THERAPEUTICS INC · CL A CUSIP 21217B100
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$16.4M1,255,5920.3%
—PALISADE BIO INC · COM CUSIP 696389402
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$15.6M8,928,1490.3%
—OCULIS HOLDING AG · ORDINARY SHARES CUSIP H5870P102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$13.1M493,8270.3%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)IRHYTHM HOLDINGS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$12.4M105,0260.2%
—ADAGIO MED HLDGS INC · COM CUSIP 00534B100
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$11.0M9,876,5760.2%
—EVOMMUNE INC · COM SHS CUSIP 30054Y107
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$10.3M448,3500.2%
—PHATHOM PHARMACEUTICALS INC · COM CUSIP 71722W107
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$10.3M925,0000.2%
—NEUMORA THERAPEUTICS INC. · COM CUSIP 640979100
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$10.0M5,104,0970.2%
—OMADA HEALTH INC · COM CUSIP 68170A108
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$9.9M786,3300.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)NEUROCRINE BIOSCIENCES INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$8.6M65,0500.2%
—BETA BIONICS INC · COM CUSIP 08659B102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$8.4M842,9440.2%
—OPUS GENETICS INC · COM CUSIP 67577R102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$8.4M1,835,8420.2%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)BILLIONTOONE INC · CL A CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$7.2M91,8120.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)TWIST BIOSCIENCE CORP · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$7.1M150,0000.1%
—SURROZEN INC
2 positions · 2 reported rows
Rows PERCEPTIVE ADVISORS LLC reported for SURROZEN INC, as it reported them
SURROZEN INC · COM NEW CUSIP 86889P208 $6.7M229,393
SURROZEN INC · *W EXP 08/01/203 CUSIP 86889P117 $2.7K166,666
ticker not yet mapped
$6.7M396,0590.1%
—AGOMAB THERAPEUTICS NV · SPONSORED ADS CUSIP 00860C102
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$6.3M600,0000.1%
—EVOLUS INC · COM CUSIP 30052C107
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$5.3M1,286,8620.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)COGENT BIOSCIENCES INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$4.7M121,0820.1%
—OCULAR THERAPEUTIX INC · COM · CALL CUSIP 67576A100
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$4.2M500,0000.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ADMA BIOLOGICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$4.2M467,2330.1%
—INHIBIKASE THERAPEUTICS INC · COM NEW CUSIP 45719W205
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$3.9M2,315,0000.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CRESCENT BIOPHARMA INC. · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$3.8M206,9420.1%
—APELLIS PHARMACEUTICALS INC · COM CUSIP 03753U106
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$3.3M80,9560.1%
—OUTSET MED INC · COM NEW CUSIP 690145206
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$3.2M833,3330.1%
—EDESA BIOTECH INC · COM NEW CUSIP 27966L306
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$2.9M563,2390.1%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)ADAPTIVE BIOTECHNOLOGIES COR · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$2.1M152,5000.0%
—AVALO THERAPEUTICS INC · COM NEW CUSIP 05338F306
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$2.1M139,6670.0%
—CONNECT BIOPHARMA HLDGS LTD · SHS CUSIP G23549101
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$2.1M792,6960.0%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)CORCEPT THERAPEUTICS INC · COM CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$2.0M50,0000.0%
verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)MEDLINE INC · COM CL A CUSIP —
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
$1.2M28,0000.0%
—PALATIN TECHNOLOGIES INC · COM NEW CUSIP 696077601
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$1.1M61,9450.0%
—CUMBERLAND PHARMACEUTICALS I · COM CUSIP 230770109
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$640K196,9780.0%
—EXAGEN INC · COM CUSIP 30068X103
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$345K114,8930.0%
—ENSYSCE BIOSCIENCES INC · COM NEW CUSIP 293602504
quarter ended 2026-03-31 filed filed 2026-05-29 +59d
ticker not yet mapped
$46.7K86,6660.0%

1–20 of 91 issuers

Change kind and share change are in Position changes above; Congress overlap is planned.

1–91 of 91 issuers · page 1 of 1
One line per issuer, largest first; a row with no issuer key stands on its own line. Open a line for its rows as this filer reported them. The list holds every row this filer reported for the quarter. Issuer totals on the holders pages count each manager's own report once; that never removes a row here. how positions are grouped ↗

Book shape

2026-03-31 · concentration · vs tracked median · tick = median
Top-25 concentration
77.2%below median 80.0%
Concentration index
410 bpsbelow median 446 bps
Positions with value
94 / 94median book 97.5 positions

Concentration uses reported 13F long value, not total assets. The index is withheld when any position lacks a value. Medians are over the 8,748 tracked filers with a 2026-03-31 book; the index median over the 8,662 with a complete book.

holdings whose <value> did not parse — retained and counted, never zero-filled: 0 · share of the period's disclosed value held in the top-N positions; denominator is reported 13F value, not total assets: 77.2% · integer Herfindahl–Hirschman index in basis points over disclosed position values: 410 · QoQ moves: 136

Filing history

AVAILABLE QUARTERS
Available filing periods
PeriodSource
2026-03-31EDGAR ↗

PLANNED sector rotation · Congress overlap · signals for this filer

Complete source filings on SEC EDGAR

The complete filing on EDGAR.

The position list above is served from the published Public Filings build, each position as this filer reported it; where the page cannot embed every reported row, the list says how many it leaves out. This block is provenance, not a substitute: the filing itself is the record, and it is one click away. Public Filings decided on 2026-08-01 to serve this list from its published build; filings newer than this build are on EDGAR.

Open PERCEPTIVE ADVISORS LLC's 13F filings on SEC EDGAR ↗
Notes on this data

Quarter-end holdings as filed

Explore the full published position list and its source filing. This record excludes the manager’s cash, shorts and non-13(f) assets.

Compare consecutive quarters

Position changes retain the producer’s classification and comparability flags. Share counts and reported values describe different changes.

A snapshot, not current holdings

Use the quarter selector to inspect available periods. Unknown values stay unknown and each table states its coverage.

A 13F is a quarterly, long-only snapshot filed up to 45 days late — not current holdings. what a 13F covers ↗

13F reports cover LONG positions in Section 13(f) securities (US exchange-traded equities plus reportable options, warrants, certain convertibles) held by managers with at least $100M in such securities — so managers below that threshold are absent entirely. No short positions, no cash, no non-13(f) assets — not a full portfolio, and not a census of institutional ownership.

Positions are quarter-end snapshots filed up to 45 days late — not current holdings. A position may have been changed or closed before you ever see it, and is older still by however long ago that quarter ended.

Values are the manager's stated market value at quarter-end in era-dependent units (whole dollars for form versions effective 2023-01-03 onward, thousands before), normalized here to whole dollars with unit_basis carried on every record.

Affiliated managers may report the same position (otherManager), so one position can appear under more than one filer.

Positions under confidential treatment may be omitted until a later amendment discloses them.

These are disclosures, not investment advice (ARCHITECTURE.md §5.2 / M2-CONTRACT §5).