ORBIMED ADVISORS LLC

$5.0B reported 13(f) long value · latest quarter 2026-03-31 · CIK 1055951 · EDGAR ↗

sum of disclosed values for 2026-03-31; 0 positions carry a NULL value and are excluded from the sum, surfaced here rather than folded away: $5.0B
ALL retained default holdings for this (filer, period), including NULL-value ones: 114
positions with no comparable holding in the prior quarter (kind new), 2026-03-31: 29
positions absent from this quarter's filing after being held last quarter (kind exit), 2026-03-31 — inferred from absence, not a sale record: 23

A quarter-end snapshot. Filed up to 45 days later, so this page is not current holdings and never a complete portfolio. what a 13F is — and is not ↓ methodology §13F ↗

Position changes — into 2026-03-31

by shares · Δ value · filing link · how changes are classified §

Position changes into quarter 2026-03-31
position matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match `identity_reconciled_by_cusip`	the reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGE `classified_by_value` · EXIT = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · NO CHANGE = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an ADD or a TRIM (NEW / ADD / TRIM / EXIT / NO CHANGE) · NO PRIOR = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stake	derived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zero	reported unit changed across the pair (SH↔PRN); the share delta is withheld rather than fabricated `shares_unit_mismatch`	Prev value	Curr value	Prev shares	Curr shares
position key `sid:sec:prov:31c206ab1e048e67310a663bad5460c4` · issuer key `cusip6:B5950S` SHS NEW CALL	NEW	+$286M	+124,306,000	$0	$286M	—	124,306,000
position key `pos:15863` · issuer key `iss:1123` COM	TRIM	−$106M	−64,400	$324M	$218M	301,200	236,800
position key `sid:sec:prov:d86675a138fe55e9b9a919f196c045ad` · issuer key `cusip6:05380C` COM CALL	NEW	+$154M	+40,966,100	$0	$154M	—	40,966,100
position key `pos:14095` · issuer key `iss:307` COM	TRIM	−$81.2M	−37,200	$231M	$149M	2,419,300	2,382,100
position key `pos:10212` · issuer key `iss:1665` COM	TRIM	−$5.0M	−30,953	$147M	$142M	3,561,655	3,530,702
position key `pos:17695` · issuer key `iss:2037` ORD	NEW	+$132M	+670,200	$0	$132M	—	670,200
position key `pos:15236` · issuer key `iss:1264` COM PRN	NEW	+$123M	+125,000,000	$0	$123M	—	125,000,000
position key `sid:sec:prov:1910147dd0682cb840152de5838d5484` · issuer key `cusip6:55287L` COM	TRIM	−$15.5M	−297,316	$124M	$109M	3,935,203	3,637,887
position key `pos:17260` · issuer key `iss:165` SPONSORED ADR	TRIM	−$22.8M	−9,100	$123M	$100.0M	146,000	136,900
position key `pos:16440` · issuer key `iss:637` COM	TRIM	−$58.6M	−612,300	$157M	$98.5M	1,842,900	1,230,600
position key `pos:16805` · issuer key `iss:997` COM NEW	TRIM	−$53.0M	−54,700	$149M	$96.2M	263,400	208,700
position key `pos:17751` · issuer key `iss:1214` COM	NEW	+$79.8M	+663,400	$0	$79.8M	—	663,400
position key `sid:sec:prov:862b191ccb923fc424f39385b48ce4f8` · issuer key `cusip6:86366E` SPONSORED ADS	ADD	−$9.7M	+313,600	$80.8M	$71.1M	1,161,803	1,475,403
position key `pos:11549` · issuer key `iss:429` COM	TRIM	+$1.2M	−568,283	$63.0M	$64.2M	1,516,550	948,267
position key `pos:12517` · issuer key `iss:1997` COM	ADD	+$41.6M	+612,771	$20.0M	$61.6M	447,200	1,059,971
position key `pos:15220` · issuer key `iss:1725` COM	TRIM	−$54.3M	−142,500	$114M	$60.0M	325,000	182,500
position key `pos:15008` · issuer key `iss:318` COM	ADD	+$14.3M	+150,000	$41.8M	$56.1M	775,000	925,000
position key `sid:sec:prov:d00159df48fd34cc806ae902a076ba0a` · issuer key `cusip6:603170` COM	ADD	+$20.0M	+1,072,500	$35.6M	$55.6M	980,400	2,052,900
position key `pos:11142` · issuer key `iss:1475` COM NEW	ADD	+$27.7M	+78,000	$27.9M	$55.6M	94,500	172,500
position key `pos:10790` · issuer key `iss:1444` COM	ADD	+$13.5M	+293,600	$41.2M	$54.7M	1,652,900	1,946,500
position key `pos:13703` · issuer key `iss:619` COM	ADD	+$9.8M	+715,700	$43.1M	$52.9M	2,202,184	2,917,884
position key `pos:13186` · issuer key `iss:1273` COM	TRIM	−$31.4M	−103,800	$83.8M	$52.4M	365,800	262,000
position key `pos:12364` · issuer key `iss:26` SPONSORED ADS	ADD	+$2.2M	+97,800	$49.6M	$51.9M	367,900	465,700
position key `pos:15144` · issuer key `iss:556` COM	TRIM	−$18.2M	−34,000	$68.6M	$50.4M	299,800	265,800
position key `pos:14212` · issuer key `iss:396` COM	TRIM	−$33.9M	−309,200	$84.1M	$50.2M	3,116,011	2,806,811
position key `pos:15965` · issuer key `iss:175` SPONSORED ADR	ADD	+$5.0M	+10,000	$36.7M	$41.6M	171,977	181,977
position key `sid:sec:prov:d86675a138fe55e9b9a919f196c045ad` · issuer key `cusip6:05380C` COM PRN	NEW	+$40.5M	+40,500,000	$0	$40.5M	—	40,500,000
position key `pos:17626` · issuer key `iss:860` COM	NEW	+$40.2M	+435,200	$0	$40.2M	—	435,200
position key `pos:15131` · issuer key `iss:87` COM	TRIM	−$75.5M	−169,800	$115M	$39.4M	288,800	119,000
position key `pos:13067` · issuer key `iss:210` COM	TRIM	−$10.1M	−39,200	$46.2M	$36.2M	253,121	213,921
position key `pos:11075` · issuer key `iss:2299` SHS	ADD	+$17.3M	+1,398,749	$17.6M	$34.9M	737,400	2,136,149
position key `pos:10700` · issuer key `iss:1374` COM	TRIM	+$4.3M	−947,827	$29.8M	$34.1M	3,641,756	2,693,929
position key `pos:15047` · issuer key `iss:135` COM	ADD	−$1.2M	+15,600	$34.7M	$33.6M	99,100	114,700
position key `sid:sec:prov:0492e747c8d37a4dab1ade9330576c2c` · issuer key `cusip6:75955J` COM	ADD	+$20.2M	+2,105,264	$12.6M	$32.8M	2,610,600	4,715,864
position key `pos:17822` · issuer key `iss:1820` COM	TRIM	−$10.7M	−736,300	$39.9M	$29.3M	3,190,700	2,454,400
position key `pos:16039` · issuer key `iss:686` COM	ADD	+$6.9M	+4,604,802	$22.1M	$29.0M	5,965,498	10,570,300
position key `sid:sec:prov:3402bbe7c4ba34aeef0c97588550f290` · issuer key `cusip6:641288` COM	TRIM	−$9.6M	−309,808	$37.2M	$27.6M	2,406,335	2,096,527
position key `pos:16702` · issuer key `iss:1556` COM	ADD	+$1.6M	+74,300	$25.7M	$27.3M	239,800	314,100
position key `sid:sec:prov:eb359106a5c4d721cdc955ced4da0795` · issuer key `cusip6:87164F` COM	NEW	+$22.5M	+962,300	$0	$22.5M	—	962,300
position key `pos:18251` · issuer key `iss:315` COM	ADD	+$2.9M	+9,300	$18.3M	$21.2M	488,500	497,800
position key `sid:sec:prov:bd4b862f6cf27f7bbb6f4d26443faaca` · issuer key `cusip6:52886X` COM	ADD	−$423K	+1,477,450	$21.1M	$20.7M	2,125,000	3,602,450
position key `sid:sec:prov:c4149a9e14976bb08df8d6a0cb6dd6b6` · issuer key `cusip6:869367` COM SHS	NEW	+$20.0M	+801,144	$0	$20.0M	—	801,144
position key `sid:sec:prov:8689270ade82a464b05b5b23e79f9006` · issuer key `cusip6:640268` COM NEW	NEW	+$19.8M	+275,000	$0	$19.8M	—	275,000
position key `sid:sec:prov:f9e727b82dcd40853324f87329f6f70c` · issuer key `cusip6:23256X` COM NEW	TRIM	−$13.0M	−7,657	$31.4M	$18.4M	3,840,500	3,832,843
position key `pos:16881` · issuer key `iss:1079` COM	TRIM	−$11.7M	−50,700	$29.5M	$17.8M	119,800	69,100
position key `sid:sec:prov:306a1219dc3e80453ba2cb392e4281b0` · issuer key `cusip6:697947` COM	NEW	+$16.8M	+134,600	$0	$16.8M	—	134,600
position key `sid:sec:prov:5a62f5a6c6af34d0bbacafc0158bd77f` · issuer key `cusip6:21833P` COM NEW	ADD	+$3.3M	+140,000	$13.0M	$16.3M	1,597,287	1,737,287
position key `pos:16675` · issuer key `iss:563` COM SHS	NEW	+$15.2M	+804,000	$0	$15.2M	—	804,000
position key `sid:sec:prov:c6f0567aff349dfe2dab4a6ee5ba8988` · issuer key `cusip6:92337R` CL A	ADD	−$3.0M	+16,096	$17.9M	$14.9M	353,500	369,596
position key `pos:11671` · issuer key `iss:122` COM	NEW	+$14.0M	+39,900	$0	$14.0M	—	39,900
position key `pos:12603` · issuer key `iss:74` COM	NEW	+$13.9M	+791,000	$0	$13.9M	—	791,000
position key `sid:sec:prov:dcfd7178444c2349b987cfc50b6bf1d8` · issuer key `cusip6:30233G` COM NEW	TRIM	−$31.3M	−1,399,167	$45.1M	$13.8M	2,468,314	1,069,147
position key `sid:sec:prov:7f79da9ff584753bfd1b9acc24c00236` · issuer key `cusip6:47103J` COM	TRIM	−$13.3M	−970,826	$27.0M	$13.7M	1,954,426	983,600
position key `pos:15075` · issuer key `iss:265` COM	TRIM	−$18.1K	−316,600	$13.6M	$13.6M	1,741,800	1,425,200
position key `sid:sec:prov:b23dd6a0ecec2737a5c87e9c74cf430d` · issuer key `cusip6:055477` COM	ADD	+$9.8M	+458,200	$3.5M	$13.3M	209,100	667,300
position key `sid:sec:prov:09a6575686667c84597e4fe2b4841977` · issuer key `cusip6:09077V` COM	TRIM	+$2.0M	−79,090	$10.5M	$12.4M	790,901	711,811
position key `pos:17421` · issuer key `iss:475` COM	TRIM	−$780K	−48,900	$13.2M	$12.4M	371,000	322,100
position key `pos:16159` · issuer key `iss:94` COM	TRIM	+$1.3M	−554,567	$10.8M	$12.1M	1,102,730	548,163
position key `pos:15140` · issuer key `iss:1537` COM	NEW	+$11.4M	+14,700	$0	$11.4M	—	14,700
position key `pos:11450` · issuer key `iss:267` COM	NEW	+$11.3M	+61,600	$0	$11.3M	—	61,600
position key `pos:13592` · issuer key `iss:2297` ORD SHARES CALL	NEW	+$10.0M	+250,000	$0	$10.0M	—	250,000
position key `pos:13344` · issuer key `iss:2148` ORD SHS CL A	TRIM	+$974K	−6,600	$7.7M	$8.7M	187,199	180,599
position key `pos:16075` · issuer key `cusip6:492327` COM	TRIM	−$8.0M	−45,057	$16.4M	$8.4M	804,212	759,155
position key `pos:10600` · issuer key `iss:821` COM	NEW	+$8.3M	+59,600	$0	$8.3M	—	59,600
position key `sid:sec:prov:bf8ba8a176478fa55a6137c9e08e0ee6` · issuer key `cusip6:427746` COM	NEW	+$7.9M	+9,816,940	$0	$7.9M	—	9,816,940
position key `sid:sec:prov:37b91915f07af95197894a79df85a91e` · issuer key `cusip6:05338F` COM NEW	TRIM	−$14.5M	−712,135	$21.6M	$7.1M	1,187,300	475,165
position key `sid:sec:prov:ab98bdc5d9f0946c8554aa4745533ba5` · issuer key `cusip6:878972` COM	TRIM	−$5.0M	−348,000	$12.0M	$7.0M	574,600	226,600
position key `sid:sec:prov:88f799da4526ad1ae0a440740a6e9c1b` · issuer key `cusip6:20451W` SPONSORED ADS	NEW	+$6.4M	+1,150,646	$0	$6.4M	—	1,150,646
position key `sid:sec:prov:306a1219dc3e80453ba2cb392e4281b0` · issuer key `cusip6:697947` COM CALL	NEW	+$6.2M	+50,000	$0	$6.2M	—	50,000
position key `sid:sec:prov:cfab5f07b0b6fc7e17744bf457f942d7` · issuer key `cusip6:00166B` COM	NEW	+$5.7M	+2,866,256	$0	$5.7M	—	2,866,256
position key `pos:17947` · issuer key `iss:540` COM	NEW	+$5.5M	+151,000	$0	$5.5M	—	151,000
position key `pos:14656` · issuer key `iss:1552` COM	ADD	+$3.0M	+26,100	$2.1M	$5.1M	25,900	52,000
position key `sid:sec:prov:8da00f0cae7aab2e87fae6f0ec349fcf` · issuer key `cusip6:H0036K` SHS	TRIM	−$15.6M	−4,504,828	$20.6M	$4.9M	5,822,854	1,318,026
position key `pos:13950` · issuer key `iss:1497` COM	ADD	+$2.5M	+20,400	$1.9M	$4.4M	21,700	42,100
position key `sid:sec:prov:fefbed769ea5db09695bd4a0f3004463` · issuer key `cusip6:696389` COM	ADD	−$315K	+461,580	$4.4M	$4.1M	1,871,420	2,333,000
position key `sid:sec:prov:d8f1dce881f876173d775baaae476159` · issuer key `cusip6:02157Q` COM SHS	ADD	+$1.5M	+42,500	$2.2M	$3.8M	125,000	167,500
position key `sid:sec:prov:2bc6a25d40cf07124e3a03bdecf4a4df` · issuer key `cusip6:805111` COM	NEW	+$3.5M	+635,000	$0	$3.5M	—	635,000
position key `pos:12625` · issuer key `iss:544` COM	TRIM	+$659K	−27,000	$2.8M	$3.5M	270,006	243,006
position key `sid:sec:prov:9c654c0b85e21e330a7ebfd2ced217c7` · issuer key `cusip6:834203` COM CALL	NEW	+$3.3M	+100,000	$0	$3.3M	—	100,000
position key `pos:17611` · issuer key `iss:1399` COM	ADD	+$1.6M	+25,900	$1.8M	$3.3M	23,200	49,100
position key `pos:15121` · issuer key `iss:1122` COM	NEW	+$3.2M	+500,000	$0	$3.2M	—	500,000
position key `sid:sec:prov:fed138ced9737b90542a54b9484d2da0` · issuer key `cusip6:10919W` COM NEW	NEW	+$2.9M	+40,000	$0	$2.9M	—	40,000
position key `sid:sec:prov:3b4a08cf659449a1ac1d2ee41e501b50` · issuer key `cusip6:008064` COM NEW	TRIM	−$5.6M	−346,152	$8.2M	$2.6M	531,163	185,011
position key `sid:sec:prov:d5b8ae591253ff1bf9b2d55cf805085a` · issuer key `cusip6:12529R` COM STK	TRIM	−$431K	−548,549	$2.7M	$2.3M	1,404,902	856,353
position key `sid:sec:prov:d86675a138fe55e9b9a919f196c045ad` · issuer key `cusip6:05380C` COM	NEW	+$2.0M	+544,895	$0	$2.0M	—	544,895
position key `pos:10126` · issuer key `cusip6:483497` COM	TRIM	−$4.3M	−288,000	$6.2M	$1.9M	382,400	94,400
position key `pos:12610` · issuer key `iss:183` COM SHS	NEW	+$1.2M	+347,000	$0	$1.2M	—	347,000
pos:10390	EXIT‡e	−$8.5M	−85,664	$8.5M	$0	85,664	—
pos:10610	EXIT‡e	−$12.6M	−154,400	$12.6M	$0	154,400	—
pos:11462	EXIT‡e	−$44.6M	−314,240	$44.6M	$0	314,240	—
pos:11955	EXIT‡e	−$26.2M	−555,789	$26.2M	$0	555,789	—
pos:13488	EXIT‡e	−$14.4M	−2,380,715	$14.4M	$0	2,380,715	—
pos:14207	EXIT‡e	−$4.4M	−25,400	$4.4M	$0	25,400	—
pos:15016	EXIT‡e	−$51.3M	−105,200	$51.3M	$0	105,200	—
pos:15492	EXIT‡e	−$56.4M	−205,000	$56.4M	$0	205,000	—
position key `pos:16440` · issuer key `iss:637` COM CALL	EXIT‡e	−$12.8M	−150,000	$12.8M	$0	150,000	—
pos:17472	EXIT‡e	−$87.0M	−2,153,300	$87.0M	$0	2,153,300	—
pos:17657	EXIT‡e	−$47.5M	−2,190,907	$47.5M	$0	2,190,907	—
sid:sec:prov:0983c227d7f489fadce1abda0a417532	EXIT‡e	−$55.6M	−1,642,891	$55.6M	$0	1,642,891	—
sid:sec:prov:16b2967c1b0bb76b6346bfde109e0bb6	EXIT‡e	−$15.0M	−3,525,650	$15.0M	$0	3,525,650	—

Flags: no row carries a flag.

1–20 of the 100 changes on this page

Mark-to-market only (no share change) · 26

Positions whose share count is identical in both quarters; the value changed with price, not with a decision.

Positions held with no share change into quarter 2026-03-31
position matched across quarters by exact reported CUSIP over a registry gap — producer-reconciled identity, never a name match `identity_reconciled_by_cusip`	the reported share count is unchanged across the pair; this build's data classified the change from its reported value; builds from 2026-09-10 on read it as NO CHANGE `classified_by_value` · EXIT = absent this quarter: disposed, delisted, under confidential treatment, or reported instead by an affiliated manager — the filing does not say which · change not classifiable: value undisclosed on one side of the quarter pair, or neither shares nor value can classify it · NO CHANGE = the share count is identical in both quarters; the value moved only with price, so the row is mark-to-market and never an ADD or a TRIM (NEW / ADD / TRIM / EXIT / NO CHANGE) · NO PRIOR = this filer has no comparable holdings list for the previous quarter on record — a first filing under this registration, or a quarter reported inside an affiliated manager's filing — so the position is not called a new stake	derived by Public Filings from the published aggregate; NULL means the source did not disclose a usable value — never zero	Prev value	Curr value	Prev shares	Curr shares
position key `pos:11808` · issuer key `iss:635` COM	NO CHANGE	+$104M	$385M	$489M	15,518,492	15,518,492
position key `sid:sec:prov:bf437640b37b30ed62d091e5e9de5808` · issuer key `cusip6:29337E` COM	NO CHANGE	+$189M	$123M	$312M	7,959,538	7,959,538
position key `sid:sec:prov:e9ff346d3a780b35a7173825a62fa6c7` · issuer key `cusip6:P8696W` SHS	NO CHANGE	$0	$184M	$184M	2,718,735	2,718,735
position key `sid:sec:prov:990effbc09610fc927e1edc54d252d9d` · issuer key `cusip6:221015` COM	NO CHANGE	+$49.7M	$55.2M	$105M	7,165,006	7,165,006
position key `sid:sec:prov:c5f3f37de4d48fd1b29c266e9a76eb0b` · issuer key `cusip6:20454B` COM	NO CHANGE	−$1.2M	$81.7M	$80.5M	15,219,994	15,219,994
position key `sid:sec:prov:1a78f2f31f5e82c1522796ab4aa69fd1` · issuer key `cusip6:04272N` COM	NO CHANGE	+$8.9M	$60.9M	$69.8M	3,027,328	3,027,328
position key `pos:12161` · issuer key `iss:587` COM	NO CHANGE	−$16.5M	$84.8M	$68.3M	1,067,550	1,067,550
position key `pos:10399` · issuer key `iss:1659` COM	NO CHANGE	−$30.0M	$96.6M	$66.6M	8,288,510	8,288,510
position key `sid:sec:prov:1e348df3cde91ba41d5ebeef0c53e107` · issuer key `cusip6:91678A` COM	NO CHANGE	−$103M	$155M	$51.2M	5,693,589	5,693,589
position key `sid:sec:prov:fe2d19423331278c853d3088ebb59311` · issuer key `cusip6:82024L` COM	NO CHANGE	+$17.5M	$23.0M	$40.5M	6,306,127	6,306,127
position key `sid:sec:prov:52a86e73e5ebd8fb9104a71a48f9c42d` · issuer key `cusip6:74065P` COM	NO CHANGE	+$5.7M	$31.6M	$37.3M	10,909,256	10,909,256
position key `pos:14981` · issuer key `iss:535` COM	NO CHANGE	−$10.2M	$46.5M	$36.3M	999,000	999,000
position key `sid:sec:prov:fcb734c2b01cb725ac58cb009a803c4c` · issuer key `cusip6:34962G` COM NEW	NO CHANGE	−$1.6M	$32.6M	$31.0M	1,196,955	1,196,955
position key `pos:15125` · issuer key `iss:1798` COM	NO CHANGE	−$4.1M	$26.9M	$22.9M	46,500	46,500
position key `cusip:000000000` · issuer key `cusip6:000000` NONVOTING	NO CHANGE	+$1.9M	$20.1M	$22.1M	6,210,899	6,210,899
position key `sid:sec:prov:a469da6cabfc03832e3d85a7bff09e97` · issuer key `cusip6:M96088` COM	NO CHANGE	−$4.8M	$20.5M	$15.7M	875,487	875,487
position key `sid:sec:prov:6e16936cc001cd03c5031f448ea49187` · issuer key `cusip6:746964` COM	NO CHANGE	+$7.0M	$7.5M	$14.5M	2,252,987	2,252,987
position key `pos:10682` · issuer key `cusip6:00032Q` COM	NO CHANGE	+$4.3M	$10.1M	$14.4M	4,166,000	4,166,000
position key `sid:sec:prov:fffa505a3a774087c4e5ea8679a7fc6d` · issuer key `cusip6:14280C` COM	NO CHANGE	−$4.1M	$15.5M	$11.3M	1,252,600	1,252,600
position key `sid:sec:prov:055a2567de67e3d96ef1117e9fce8ec2` · issuer key `cusip6:007002` COM NEW	NO CHANGE	−$1.7M	$8.7M	$7.0M	1,027,944	1,027,944
position key `pos:14578` · issuer key `iss:2296` COM	NO CHANGE	+$103K	$5.7M	$5.8M	205,400	205,400
position key `sid:sec:prov:4f3f0dbc6f010cb94ff5053ef428025c` · issuer key `cusip6:45779A` COM	NO CHANGE	−$470K	$5.6M	$5.1M	3,133,405	3,133,405
position key `sid:sec:prov:6db6b47119928ad4af3cf49015c9c5eb` · issuer key `cusip6:45175G` COM	NO CHANGE	−$719K	$2.6M	$1.9M	378,556	378,556
position key `sid:sec:prov:ab6da773af8f9d90bd90fe82cc6dbcd7` · issuer key `cusip6:92840H` COM	NO CHANGE	−$277K	$2.0M	$1.7M	3,060,000	3,060,000
position key `pos:14800` · issuer key `iss:475` NOTE 1.625%11/1 PRN	NO CHANGE	+$45.9K	$1.2M	$1.2M	1,000,000	1,000,000
position key `sid:sec:prov:ad5ef68a1a97fba832bc53a8b03014af` · issuer key `cusip6:68232V` COM NEW	NO CHANGE	+$424K	$684K	$1.1M	605,531	605,531

Flags: no row carries a flag.

Newest filing in this build: 2026-07-31. Per-row filing dates are on each receipt.

Truncated by Public Filings. Changes compare every position with a security identifier, new and exited included; holdings without one are counted, not compared. methodology §13F ↗

Reported positions — 2026-03-31

1–100 of 109 issuers · $5.0B disclosed value over 114 rows · 0 undisclosed-value rows

View

This build carries one quarter for this manager: 2026-03-31. Notable managers carry four published quarters, others two.

This list carries reported issuer names and security identities, without a dated ticker mapping. Symbols are not inferred from names.

a position composed from a base filing plus NEW-HOLDINGS amendments keeps every source row here; the composition's latest filed date is the one shown served from this build's published holdings (derived from the filer's own reported rows); every row resolves to its filing

Share of total reported value, calculated only when the full position list has disclosed values. This is 13F long value, not total assets.

value undisclosed on the filing: retained and counted, excluded from sums, never shown as $0

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

EDGEWISE THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$489M

15,518,492

9.7%

—

ENLIVEN THERAPEUTICS INC · COM CUSIP 29337E102
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$312M

7,959,538

6.2%

—

MDXHEALTH SA · SHS NEW · CALL CUSIP B5950S113
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$286M

124,306,000

5.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ELI LILLY & CO · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$218M

236,800

4.3%

—

AVITA MEDICAL INC

3 positions · 3 reported rows

Rows ORBIMED ADVISORS LLC reported for AVITA MEDICAL INC, as it reported them
AVITA MEDICAL INC · COM · CALL CUSIP 05380C102 src ↗	$154M	40,966,100
AVITA MEDICAL INC · COM CUSIP 05380C102 src ↗	$40.5M	40,500,000 PRN
AVITA MEDICAL INC · COM CUSIP 05380C102 src ↗	$2.0M	544,895

ticker not yet mapped

$197M

—

3.9%

—

SINOVAC BIOTECH LTD · SHS CUSIP P8696W104
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$184M

2,718,735

3.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

BOSTON SCIENTIFIC CORP · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$149M

2,382,100

3.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

SIONNA THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$142M

3,530,702

2.8%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ASTRAZENECA PLC · ORD CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$132M

670,200

2.6%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

MYRIAD GENETICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$123M

125,000,000 PRN

2.4%

—

MBX BIOSCIENCES INC · COM CUSIP 55287L101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$109M

3,637,887

2.2%

—

CORVUS PHARMACEUTICALS INC · COM CUSIP 221015100
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$105M

7,165,006

2.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ARGENX SE · SPONSORED ADR CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$100.0M

136,900

2.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

EDWARDS LIFESCIENCES CORP · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$98.5M

1,230,600

2.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

INTUITIVE SURGICAL INC · COM NEW CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$96.2M

208,700

1.9%

—

COMPASS THERAPEUTICS INC · COM CUSIP 20454B104
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$80.5M

15,219,994

1.6%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

MERCK & CO INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$79.8M

663,400

1.6%

—

STRUCTURE THERAPEUTICS INC · SPONSORED ADS CUSIP 86366E106
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$71.1M

1,475,403

1.4%

—

ARRIVENT BIOPHARMA INC · COM CUSIP 04272N102
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$69.8M

3,027,328

1.4%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

DISC MEDICINE INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$68.3M

1,067,550

1.4%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ARS PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$66.6M

8,288,510

1.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

CG ONCOLOGY INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$64.2M

948,267

1.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

XENON PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$61.6M

1,059,971

1.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

STRYKER CORPORATION · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$60.0M

182,500

1.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

BRISTOL-MYERS SQUIBB CO · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$56.1M

925,000

1.1%

—

MINERALYS THERAPEUTICS INC · COM CUSIP 603170101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$55.6M

2,052,900

1.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

PRAXIS PRECISION MEDICINES I · COM NEW CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$55.6M

172,500

1.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

PFIZER INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$54.7M

1,946,500

1.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

DYNE THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$52.9M

2,917,884

1.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

NATERA INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$52.4M

262,000

1.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ABIVAX SA · SPONSORED ADS CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$51.9M

465,700

1.0%

—

UPSTREAM BIO INC · COM CUSIP 91678A107
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$51.2M

5,693,589

1.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

DANAHER CORP DEL · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$50.4M

265,800

1.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

CARIS LIFE SCIENCES INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$50.2M

2,806,811

1.0%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ASCENDIS PHARMA A/S · SPONSORED ADR CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$41.6M

181,977

0.8%

—

SHATTUCK LABS INC · COM CUSIP 82024L103
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$40.5M

6,306,127

0.8%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

GUARDANT HEALTH INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$40.2M

435,200

0.8%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ALNYLAM PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$39.4M

119,000

0.8%

—

PRELUDE THERAPEUTICS INC · COM CUSIP 74065P101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$37.3M

10,909,256

0.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

CRINETICS PHARMACEUTICALS IN · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$36.3M

999,000

0.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

AXSOME THERAPEUTICS INC. · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$36.2M

213,921

0.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

UNIQURE NV · SHS CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$34.9M

2,136,149

0.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ORIC PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$34.1M

2,693,929

0.7%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ELEVANCE HEALTH INC FORMERLY · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$33.6M

114,700

0.7%

—

RELMADA THERAPEUTICS INC · COM CUSIP 75955J402
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$32.8M

4,715,864

0.7%

—

FORTE BIOSCIENCES INC · COM NEW CUSIP 34962G208
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$31.0M

1,196,955

0.6%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

TREVI THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$29.3M

2,454,400

0.6%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ESPERION THERAPEUTICS INC NE · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$29.0M

10,570,300

0.6%

—

NEUROPACE INC · COM CUSIP 641288105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$27.6M

2,096,527

0.5%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

RHYTHM PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$27.3M

314,100

0.5%

—

PALVELLA THERAPEUTICS INC NE

2 positions · 2 reported rows

Rows ORBIMED ADVISORS LLC reported for PALVELLA THERAPEUTICS INC NE, as it reported them
PALVELLA THERAPEUTICS INC NE · COM CUSIP 697947109 src ↗	$16.8M	134,600
PALVELLA THERAPEUTICS INC NE · COM · CALL CUSIP 697947109 src ↗	$6.2M	50,000

ticker not yet mapped

$23.0M

184,600

0.5%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

THERMO FISHER SCIENTIFIC INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$22.9M

46,500

0.5%

—

SYNDAX PHARMACEUTICALS INC · COM CUSIP 87164F105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$22.5M

962,300

0.4%

—

PRELUDE THERAPEUTICS INC

1 position · 2 reported rows

Rows ORBIMED ADVISORS LLC reported for PRELUDE THERAPEUTICS INC, as it reported them
PRELUDE THERAPEUTICS INC · NONVOTING CUSIP 000000000 src ↗	$19.4M	5,680,186
IMAGENEBIO INC · NONVOTING CUSIP 000000000 src ↗	$2.7M	530,713

ticker not yet mapped

$22.1M

6,210,899

0.4%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

BRIGHTSPRING HEALTH SVCS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$21.2M

497,800

0.4%

—

LEXEO THERAPEUTICS INC · COM CUSIP 52886X107
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$20.7M

3,602,450

0.4%

—

SUTRO BIOPHARMA INC · COM SHS CUSIP 869367201
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$20.0M

801,144

0.4%

—

NEKTAR THERAPEUTICS · COM NEW CUSIP 640268306
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$19.8M

275,000

0.4%

—

CYBIN INC · COM NEW CUSIP 23256X407
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$18.4M

3,832,843

0.4%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

KRYSTAL BIOTECH INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$17.8M

69,100

0.4%

—

CORBUS PHARMACEUTICALS HLDGS · COM NEW CUSIP 21833P301
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$16.3M

1,737,287

0.3%

—

UROGEN PHARMA LTD · COM CUSIP M96088105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$15.7M

875,487

0.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

DEFINIUM THERAPEUTICS INC · COM SHS CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$15.2M

804,000

0.3%

—

VERA THERAPEUTICS INC · CL A CUSIP 92337R101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$14.9M

369,596

0.3%

—

Q32 BIO INC · COM CUSIP 746964105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$14.5M

2,252,987

0.3%

—

WHITEHAWK THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$14.4M

4,166,000

0.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

AMGEN INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$14.0M

39,900

0.3%

—

ALIGNMENT HEALTHCARE INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$13.9M

791,000

0.3%

—

EYEPOINT INC · COM NEW CUSIP 30233G209
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$13.8M

1,069,147

0.3%

—

JANUX THERAPEUTICS INC · COM CUSIP 47103J105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$13.7M

983,600

0.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

COGENT BIOSCIENCES INC

2 positions · 2 reported rows

Rows ORBIMED ADVISORS LLC reported for COGENT BIOSCIENCES INC, as it reported them
COGENT BIOSCIENCES INC · COM CUSIP — src ↗	$12.4M	322,100
COGENT BIOSCIENCES INC · NOTE 1.625%11/1 CUSIP — src ↗	$1.2M	1,000,000 PRN

$13.6M

—

0.3%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

BIOCRYST PHARMACEUTICALS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$13.6M

1,425,200

0.3%

—

BICARA THERAPEUTICS INC · COM CUSIP 055477103
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$13.3M

667,300

0.3%

—

BIOAGE LABS INC · COM CUSIP 09077V100
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$12.4M

711,811

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ALUMIS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$12.1M

548,163

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

REGENERON PHARMACEUTICALS · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$11.4M

14,700

0.2%

—

CARLSMED INC · COM CUSIP 14280C105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$11.3M

1,252,600

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

BIOGEN INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$11.3M

61,600

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

QIAGEN NV · ORD SHARES · CALL CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$10.0M

250,000

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

KINIKSA PHARMACEUTICALS INTL · ORD SHS CL A CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$8.7M

180,599

0.2%

—

KEROS THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$8.4M

759,155

0.2%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

GILEAD SCIENCES INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$8.3M

59,600

0.2%

—

HERON THERAPEUTICS INC · COM CUSIP 427746102
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$7.9M

9,816,940

0.2%

—

AVALO THERAPEUTICS INC · COM NEW CUSIP 05338F306
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$7.1M

475,165

0.1%

—

TECTONIC THERAPEUTIC INC · COM CUSIP 878972108
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$7.0M

226,600

0.1%

—

ADICET BIO INC · COM NEW CUSIP 007002207
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$7.0M

1,027,944

0.1%

—

COMPASS PATHWAYS PLC · SPONSORED ADS CUSIP 20451W101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$6.4M

1,150,646

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

PHARVARIS N V · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$5.8M

205,400

0.1%

—

ALX ONCOLOGY HLDGS INC · COM CUSIP 00166B105
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$5.7M

2,866,256

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

ARTIVION INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$5.5M

151,000

0.1%

—

INSPIREMD INC · COM CUSIP 45779A846
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$5.1M

3,133,405

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

REVOLUTION MEDICINES INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$5.1M

52,000

0.1%

—

ADC THERAPEUTICS SA · SHS CUSIP H0036K147
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$4.9M

1,318,026

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

PROTAGONIST THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$4.4M

42,100

0.1%

—

PALISADE BIO INC · COM CUSIP 696389402
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$4.1M

2,333,000

0.1%

—

ALTO NEUROSCIENCE INC · COM SHS CUSIP 02157Q109
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$3.8M

167,500

0.1%

—

SAVARA INC · COM CUSIP 805111101
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$3.5M

635,000

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

CULLINAN THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$3.5M

243,006

0.1%

—

SOLENO THERAPEUTICS INC · COM · CALL CUSIP 834203309
2026-03-31 filed 2026-05-15 +45d

src ↗

ticker not yet mapped

$3.3M

100,000

0.1%

verified against the SEC company list on 2026-09-10 — a reviewed mapping row for this filed issuer name and class (never inferred)

PTC THERAPEUTICS INC · COM CUSIP —
2026-03-31 filed 2026-05-15 +45d

src ↗

$3.3M

49,100

0.1%

1–20 of the 100 issuers on this page

Change kind and share change are in Position changes above; Congress overlap is planned.

One line per issuer, largest first; a row with no issuer key stands on its own line. Open a line for its rows as this filer reported them. The list holds every row this filer reported for the quarter. Issuer totals on the holders pages count each manager's own report once; that never removes a row here. how positions are grouped ↗

Book shape

2026-03-31 · concentration · vs tracked median · tick = median

Top-25 concentration: 66.9%below median 80.0%
Concentration index: 295 bpsbelow median 446 bps
Positions with value: 114 / 114median book 97.5 positions

Concentration uses reported 13F long value, not total assets. The index is withheld when any position lacks a value. Medians are over the 8,748 tracked filers with a 2026-03-31 book; the index median over the 8,662 with a complete book.

holdings whose <value> did not parse — retained and counted, never zero-filled: 0 · share of the period's disclosed value held in the top-N positions; denominator is reported 13F value, not total assets: 66.9% · integer Herfindahl–Hirschman index in basis points over disclosed position values: 295 · QoQ moves: 136

Filing history

AVAILABLE QUARTERS

Available filing periods
Period	Source
2026-03-31	EDGAR ↗

PLANNED sector rotation · Congress overlap · signals for this filer

Complete source filings on SEC EDGAR

The complete filing on EDGAR.

The position list above is served from the published Public Filings build, each position as this filer reported it; where the page cannot embed every reported row, the list says how many it leaves out. This block is provenance, not a substitute: the filing itself is the record, and it is one click away. Public Filings decided on 2026-08-01 to serve this list from its published build; filings newer than this build are on EDGAR.

Open ORBIMED ADVISORS LLC's 13F filings on SEC EDGAR ↗

Notes on this data

Reported positions

Quarter-end holdings as filed

Explore the full published position list and its source filing. This record excludes the manager’s cash, shorts and non-13(f) assets.

Share changes

Compare consecutive quarters

Position changes retain the producer’s classification and comparability flags. Share counts and reported values describe different changes.

Coverage

A snapshot, not current holdings

Use the quarter selector to inspect available periods. Unknown values stay unknown and each table states its coverage.

A 13F is a quarterly, long-only snapshot filed up to 45 days late — not current holdings. what a 13F covers ↗

13F reports cover LONG positions in Section 13(f) securities (US exchange-traded equities plus reportable options, warrants, certain convertibles) held by managers with at least $100M in such securities — so managers below that threshold are absent entirely. No short positions, no cash, no non-13(f) assets — not a full portfolio, and not a census of institutional ownership.

Positions are quarter-end snapshots filed up to 45 days late — not current holdings. A position may have been changed or closed before you ever see it, and is older still by however long ago that quarter ended.

Values are the manager's stated market value at quarter-end in era-dependent units (whole dollars for form versions effective 2023-01-03 onward, thousands before), normalized here to whole dollars with unit_basis carried on every record.

Affiliated managers may report the same position (otherManager), so one position can appear under more than one filer.

Positions under confidential treatment may be omitted until a later amendment discloses them.

These are disclosures, not investment advice (ARCHITECTURE.md §5.2 / M2-CONTRACT §5).